Methanesulfonyl chloride → 2-[2-(4-Chlorophenyl)ethoxy]ethyl methanesulfonate

반응식

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][O:10][CH2:11][CH2:12][OH:13])=[CH:4][CH:3]=1.[CH3:14][S:15](Cl)(=[O:17])=[O:16]>>[CH3:14][S:15]([O:13][CH2:12][CH2:11][O:10][CH2:9][CH2:8][C:5]1[CH:4]=[CH:3][C:2]([Cl:1])=[CH:7][CH:6]=1)(=[O:17])=[O:16]

참가 물질

반응물 2

HCID 31297Methanesulfonyl chloride

HCID 132089322-[2-(4-Chlorophenyl)ethoxy]ethanol

생성물 1

HCID 132108222-[2-(4-Chlorophenyl)ethoxy]ethyl methanesulfonate수율 92%

실험 절차

The 2-[2-(4-chlorophenyl)ethoxy]ethanol obtained according to the preceding paragraph was sulfonylated with methanesulfonyl chloride in a manner analogous to that described in Example 1(c) to give 1.5 g (92%) of 2-[2-(4-chlorophenyl)ethoxy]ethyl methanesulfonate in the form of an oil which was homogeneous according to chromatography.

출처 및 근거

ORD 기록: ord-84d926e077234aa0a7ee534152bcf001
출처 데이터셋: uspto-grants-1987_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04649160

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