Methyl alpha-acetamidocinnamate → Acetylphenylalanine methyl ester

HRID 1906707

반응식

HRID 1906707 반응식
[C:1]([NH:4][C:5](=[CH:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[C:6]([O:8][CH3:9])=[O:7])(=[O:3])[CH3:2]>C(OCC)(=O)C>[CH3:9][O:8][C:6](=[O:7])[C@H:5]([CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[NH:4][C:1](=[O:3])[CH3:2]

참가 물질

3

반응물 1

HCID 340163Methyl alpha-acetamidocinnamate

생성물 1

HCID 704002Acetylphenylalanine methyl ester수율 82.4%

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

실험 절차

A second recycling of the catalyst is performed under the conditions described above, but introducing methyl α-acetamidocinnamate (1.6 g) and ethyl acetate (10 cc). Pure N-acetylphenylalanine methyl ester (1.33 g) is thus obtained with a conversion of 100%, its rotatory power being:

출처 및 근거

ORD 기록
ord-e343201433b347ff99acb0176de1801c
출처 데이터셋
uspto-grants-1987_03
특허 번호
US04654176

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