1-Hexadecanol, 1-(4-methylbenzenesulfonate) → 2-Methyl-3-n-hexadecyloxy-7-n-butoxycarbonylmethylthio-pyrazolo[4,3-d]pyrimidine

HRID 1906766

반응식

HRID 1906766 반응식
[CH3:1][N:2]1[C:19]([OH:20])=[C:5]2[N:6]=[CH:7][N:8]=[C:9]([S:10][CH2:11][C:12]([O:14][CH2:15][CH2:16][CH2:17][CH3:18])=[O:13])[C:4]2=[N:3]1.C1(C)C=CC(S(O[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH3:46])(=O)=O)=CC=1>>[CH3:1][N:2]1[C:19]([O:20][CH2:46][CH2:45][CH2:44][CH2:43][CH2:42][CH2:41][CH2:40][CH2:39][CH2:38][CH2:37][CH2:36][CH2:35][CH2:34][CH2:33][CH2:32][CH3:31])=[C:5]2[N:6]=[CH:7][N:8]=[C:9]([S:10][CH2:11][C:12]([O:14][CH2:15][CH2:16][CH2:17][CH3:18])=[O:13])[C:4]2=[N:3]1

참가 물질

3

반응물 2

HCID 801711-Hexadecanol, 1-(4-methylbenzenesulfonate)HCID 178451394HCID 178451394, 화합물

생성물 1

HCID 136073632-Methyl-3-n-hexadecyloxy-7-n-butoxycarbonylmethylthio-pyrazolo[4,3-d]pyrimidine수율 75%

실험 절차

2-Methyl-3-hydroxy-7-n-butoxycarbonylmethylthiopyrazolo[4,3-d]pyrimidine and n-hexadecyl p-toluenesulfonate were reacted and treated in the same manner as in Synthesis 2 of Example 1 to obtain the desired compound.

후처리

  1. additiontreated in the same manner as in Synthesis 2 of Example 1

출처 및 근거

ORD 기록
ord-0608514a31a14a94a18126aefd3050b5
출처 데이터셋
uspto-grants-1987_03
특허 번호
US04654348

연결된 노트

불러오는 중…