Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(2,6-Xylyl)piperazine → 1-[(6-Fluoro-3-methoxyquinoxalin-2-yl)aminocarbonyl]-4-(2,6-dimethylphenyl)piperazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(2,6-Xylyl)piperazine | HCID 70538 | — |
| 반응물 | ethyl N-(6-fluoro-3-methoxyquinoxalin-2-yl)carbamate | HCID 69243333 | — |
| 생성물 | 1-[(6-Fluoro-3-methoxyquinoxalin-2-yl)aminocarbonyl]-4-(2,6-dimethylphenyl)piperazine | HCID 69243601 | 76% |
반응 단계
Ethyl N-(6-fluoro-3-methoxyquinoxalin-2-yl)carbamate and 1-(2,6-dimethylphenyl)piperazine were reacted by the same way with the example 85 to obtain the titled compound (yield, 76%). 1H NMR (300 MHz, CDCl3): δ 2.36 (s, 6H), 3.18-3.21 (m, 4H), 3.69-3.72 (m, 4H), 4.15 (s, 3H), 6.97-7.04 (m, 3H), 7.22-7.42 (m, 4H), 7.82-7.87 (m, 1H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08598173B2 |
| 출처 데이터셋 | uspto-grants-2013_12 |
| ORD ID | ord-c73cf12bbcf54f8ab0bfae429ec9e244 |
| 출처 메모 | uspto-grants-2013_12 |