1-(2-Pyridyl)piperazine → 1-[(3,6-Dimethoxyquinoxalin-2-yl)aminocarbonyl]-4-(2-pyridyl)piperazine

HRID 1907618노트

반응식

HRID 1907618 반응식
[CH3:1][O:2][C:3]1[C:4]([NH:15][C:16](=[O:20])OCC)=[N:5][C:6]2[C:11]([N:12]=1)=[CH:10][C:9]([O:13][CH3:14])=[CH:8][CH:7]=2.[N:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[N:27]1[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]1>>[CH3:1][O:2][C:3]1[C:4]([NH:15][C:16]([N:30]2[CH2:31][CH2:32][N:27]([C:22]3[CH:23]=[CH:24][CH:25]=[CH:26][N:21]=3)[CH2:28][CH2:29]2)=[O:20])=[N:5][C:6]2[C:11]([N:12]=1)=[CH:10][C:9]([O:13][CH3:14])=[CH:8][CH:7]=2

참가 물질

3

반응물 2

HCID 944591-(2-Pyridyl)piperazineHCID 69244324ethyl N-(3,6-dimethoxyquinoxalin-2-yl)carbamate

생성물 1

HCID 692434751-[(3,6-Dimethoxyquinoxalin-2-yl)aminocarbonyl]-4-(2-pyridyl)piperazine수율 94%

실험 절차

Ethyl N-(3,6-dimethoxyquinoxalin-2-yl)carbamate and 1-(2-pyridyl)piperazine were reacted by the same way with the example 148 to obtain the titled compound (yield, 94%).

출처 및 근거

ORD 기록
ord-88635ecc66204f4db4923db412cb786a
출처 데이터셋
uspto-grants-2013_12
특허 번호
US08598173B2

반응 노트

불러오는 중…