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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1908256생성일: 2026년 10월 24일

2-Amino-1-(4-fluorophenyl)ethanone → 2-Amino-1-(4-fluorophenyl)ethan-1-ol

https://huagongshe.com/ko/reaction/1908256

반응식

참여 물질

역할이름HCID투입량
반응물2-Amino-1-(4-fluorophenyl)ethanoneHCID 1581177—
반응물Sodium borohydrideHCID 4311764—
용매MethanolHCID 887—
생성물2-Amino-1-(4-fluorophenyl)ethan-1-olHCID 9827100%

반응 단계

To a solution consisting of 2-amino-1-(4-fluoro-phenyl)-ethanone (150 mg, 0.9 mmol) and MeOH (5 mL) was added NaBH4 (97 mg, 2.6 mmol). The mixture was stirred at rt for 45 min and then concentrated to dryness. The residue was diluted with EtOAc and washed with a satd. NH4Cl solution before drying (Na2SO4), and concentrating to give 2-amino-1-(4-fluoro-phenyl)-ethanol (139 mg, 100%) which was used without further purification.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08598202B2
출처 데이터셋uspto-grants-2013_12
ORD IDord-3de15211aafd4142a970ccbc6622e103
출처 메모uspto-grants-2013_12