Ethylene Glycol → 2-Hydroxyethyl ethyl(3-hydroxypropyl)phosphinate
반응식
[CH2:1]([P:3]([CH2:10][CH2:11][CH2:12][OH:13])(=[O:9])[O:4][CH2:5][CH2:6]CC)[CH3:2].C(O)C[OH:16]>C([O-])(C([O-])=O)=O.C([O-])(C([O-])=O)=O.O=[Ti+2].[K+].[K+]>[CH2:1]([P:3]([CH2:10][CH2:11][CH2:12][OH:13])(=[O:9])[O:4][CH2:5][CH2:6][OH:16])[CH3:2]참가 물질
4
반응 조건
- 온도
- 200 °C
실험 절차
To 416 g (2 mol) of butyl ethyl(3-hydroxypropyl)phosphinate (produced as in Example 11) are added 155 g (2.5 mol) of ethylene glycol and 0.4 g of potassium titanyloxalate, followed by stirring at 200° C. for 2 h. Volatiles are distilled off by gradual evacuation to leave 439 g (98% of theory) of 2-hydroxyethyl ethyl(3-hydroxypropyl)phosphinate.
후처리
- distillationVolatiles are distilled off by gradual evacuation
출처 및 근거
- ORD 기록
- ord-56ed5dce95274453a95f4d84a68c760e
- 출처 데이터셋
- uspto-grants-2013_12
- 특허 번호
- US08604108B2
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