{4-[(10-Benzyl-9,10-diazatricyclo[4.2.1.12,5]-dec-9-yl)-(3-methoxyphenyl)methyl]phenyl}-piperidin-1-yl-methanone → {4-[(9,10-Diazatricyclo[4.2.1.12,5]dec-9-yl)-(3-methoxyphenyl)-methyl]phenyl}-piperidin-1-yl-methanone
반응식
C(N1C2C3N(C(C4C=CC=C(OC)C=4)C4C=CC(C(N(CC)CC)=O)=CC=4)C(C1CC2)CC3)C1C=CC=CC=1.C([N:47]1[CH:51]2[CH:52]3[N:56]([CH:57]([C:72]4[CH:77]=[CH:76][CH:75]=[C:74]([O:78][CH3:79])[CH:73]=4)[C:58]4[CH:63]=[CH:62][C:61]([C:64]([N:66]5[CH2:71][CH2:70][CH2:69][CH2:68][CH2:67]5)=[O:65])=[CH:60][CH:59]=4)[CH:55]([CH:48]1[CH2:49][CH2:50]2)[CH2:54][CH2:53]3)C1C=CC=CC=1>>[CH:52]12[N:56]([CH:57]([C:72]3[CH:77]=[CH:76][CH:75]=[C:74]([O:78][CH3:79])[CH:73]=3)[C:58]3[CH:59]=[CH:60][C:61]([C:64]([N:66]4[CH2:67][CH2:68][CH2:69][CH2:70][CH2:71]4)=[O:65])=[CH:62][CH:63]=3)[CH:55]([CH2:54][CH2:53]1)[CH:48]1[NH:47][CH:51]2[CH2:50][CH2:49]1참가 물질
3
반응물 2
생성물 1
실험 절차
The procedure of Example 5.1 was repeated, but using instead of the compound prepared in Example 4.1 the compound {4-[(10-benzyl-9,10-diazatricyclo[4.2.1.12,5]dec-9-yl)-(3-methoxyphenyl)methyl]phenyl}-piperidin-1-yl-methanone of Example 4.3. The compound {4-[(9,10-diazatricyclo[4.2.1.12,5]dec-9-yl)-(3-methoxyphenyl)-methyl]phenyl}-piperidin-1-yl-methanone was obtained.