Cyclopropanecarbonyl chloride → Methyl 2-(cyclopropanecarboxamido)thiophene-3-carboxylate

HRID 1912518

반응식

[CH:1]1([C:4](Cl)=[O:5])[CH2:3][CH2:2]1.[NH2:7][C:8]1[S:9][CH:10]=[CH:11][C:12]=1[C:13]([O:15][CH3:16])=[O:14]>>[CH:1]1([C:4]([NH:7][C:8]2[S:9][CH:10]=[CH:11][C:12]=2[C:13]([O:15][CH3:16])=[O:14])=[O:5])[CH2:3][CH2:2]1

참가 물질

반응물 2

HCID 77637Cyclopropanecarbonyl chloride

HCID 78381Methyl 2-amino-3-thenoate

생성물 1

HCID 2808559Methyl 2-(cyclopropanecarboxamido)thiophene-3-carboxylate

실험 절차

Cyclopropanecarbonyl chloride and methyl 2-aminothiophene-3-carboxylate (Aldrich) were processed using method analogous to that described in Example 13A to afford the title compound.

출처 및 근거

ORD 기록: ord-9a273e66362b4883bb8f57a9feffba60
출처 데이터셋: uspto-grants-2013_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08609674B2

연결된 노트

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