p-Fluoronitrobenzene → 1-[4-(2-Aminopurin-9-yl)phenyl]-3-(4-chloro-3-(trifluoromethyl)phenyl)urea hydrochloride

HRID 1912781

반응식

HRID 1912781 반응식
[NH2:1][C:2]1[N:10]=[C:9]2[C:5]([NH:6][CH:7]=[N:8]2)=[CH:4][N:3]=1.F[C:12]1[CH:17]=[CH:16][C:15]([N+:18]([O-])=O)=[CH:14][CH:13]=1.[Cl:21][C:22]1[CH:27]=[CH:26][C:25]([N:28]=[C:29]=[O:30])=[CH:24][C:23]=1[C:31]([F:34])([F:33])[F:32]>>[ClH:21].[NH2:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[C:12]2[CH:17]=[CH:16][C:15]([NH:18][C:29]([NH:28][C:25]3[CH:26]=[CH:27][C:22]([Cl:21])=[C:23]([C:31]([F:33])([F:32])[F:34])[CH:24]=3)=[O:30])=[CH:14][CH:13]=2)=[CH:4][N:3]=1

참가 물질

4

실험 절차

The title compound can be synthesized from 2-aminopurine, 4-fluoronitrobenzene and 4-chloro-3-(trifluoromethyl)phenyl isocyanate by the same methods as in Examples 29 and 30.

출처 및 근거

ORD 기록
ord-36b385a907b84a55ae6f59d1f118f615
출처 데이터셋
uspto-grants-2013_12
특허 번호
US08609656B2

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