Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Cyclohexylideneacetic acid → N-(3-tert-butylpyrazolo[1,5-a]pyrimidin-2-yl)-2-cyclohexylideneacetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Cyclohexylideneacetic acid | HCID 96206 | — |
| 반응물 | 3-Tert-butylpyrazolo[1,5-a]pyrimidin-2-amine | HCID 68755471 | — |
| 생성물 | N-(3-tert-butylpyrazolo[1,5-a]pyrimidin-2-yl)-2-cyclohexylideneacetamide | HCID 68753367 | — |
반응 단계
The product from Example 105B and 2-cyclohexylideneacetic acid were processed using the method analogous to that described in Example 137 to afford the title compound. 1H NMR (300 MHz, DMSO-d6) δ ppm 1.44 (s, 9H), 1.50-1.63 (m, 6H), 2.15-2.18 (m, 2H), 2.80-2.82 (m, 2H), 5.80 (br s, 1H), 6.98 (dd, J=6.8, 4.1 Hz, 1H), 8.48 (dd, J=4.1, 2.0 Hz, 1H), 8.91 (dd, J=7.1, 1.7 Hz, 1H), 9.58 (br s, 1H); MS (DCI) m/z 313 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08609669B2 |
| 출처 데이터셋 | uspto-grants-2013_12 |
| ORD ID | ord-ba2a614f52be4f9cae11d9c54690e7d7 |
| 출처 메모 | uspto-grants-2013_12 |