(4-Chloro-2-methylphenyl)boronic acid → 3-Amino-6-(4-chloro-2-methyl-phenyl)-5-trifluoromethyl-pyridine-2-carboxylic acid methyl ester

HRID 191416

반응식

HRID 191416 반응식
[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][c:7]([Br:16])[c:8]([C:12]([F:13])([F:14])[F:15])[cH:9][c:10]1[NH2:11].[Cl:17][c:18]1[cH:19][c:20]([CH3:27])[c:21]([B:24]([OH:25])[OH:26])[cH:22][cH:23]1>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][c:7](-[c:21]2[c:20]([CH3:27])[cH:19][c:18]([Cl:17])[cH:23][cH:22]2)[c:8]([C:12]([F:13])([F:14])[F:15])[cH:9][c:10]1[NH2:11]

참가 물질

3

반응물 2

HCID 5017600(4-Chloro-2-methylphenyl)boronic acidHCID 58964428Methyl 3-amino-6-bromo-5-(trifluoromethyl)picolinate

생성물 1

HCID 584423533-Amino-6-(4-chloro-2-methyl-phenyl)-5-trifluoromethyl-pyridine-2-carboxylic acid methyl ester

출처 및 근거

ORD 기록
ord-9a55b53d28204e5bbefdf52c014f6165
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

연결된 노트

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