3,5-Diamino-1,2,4-triazole → HCID 178508251, 화합물

HRID 1915597노트

반응식

HRID 1915597 반응식
[NH2:1][C:2]1[N:6]=[C:5]([NH2:7])[NH:4][N:3]=1.[C:8]1([CH:14]([C:20](OCC)=[O:21])[C:15](OCC)=[O:16])[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>C(N(CCCC)CCCC)CCC>[NH2:1][C:2]1[N:6]=[C:5]2[N:7]=[C:15]([OH:16])[C:14]([C:8]3[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=3)=[C:20]([OH:21])[N:4]2[N:3]=1

참가 물질

4

반응물 2

HCID 150783,5-Diamino-1,2,4-triazoleHCID 66514Diethyl phenylmalonate

생성물 1

HCID 178508251HCID 178508251, 화합물

시약·촉매·용매 1

HCID 7622Tributylamine용매

실험 절차

A solution of 9.0 g 3,5-diamino-1,2,4-triazole and 22.4 ml diethyl phenylmalonate in N,N-dibutylbutan-1-amine is heated under microwave irradiation to 180° C. for 8 h. The reaction mixture forms two layers after cooling to room temperature. The top layer is removed and the solvent of the lower layer is evaporated. The residue is treated with water and acidified with 5N HCl. The precipitated product is collected by filtration and dried. The crude product is used without further purification.

후처리

  1. customThe top layer is removed
  2. customthe solvent of the lower layer is evaporated
  3. additionThe residue is treated with water
  4. filtrationThe precipitated product is collected by filtration
  5. customdried
  6. customThe crude product is used without further purification

출처 및 근거

ORD 기록
ord-0264d4253e5240c2aa2fede970219094
출처 데이터셋
uspto-grants-2013_12
특허 번호
US08614218B2

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