5-(4-Chloro-phenyl)-2-ethynyl-pyridine → HCID 59835855, 화합물

HRID 1916624노트

반응식

HRID 1916624 반응식
I[C:2]1[N:6]([CH3:7])[C:5]2[CH:8]=[CH:9][C:10]([CH2:12][N:13]3[CH2:17][CH2:16][CH2:15][CH2:14]3)=[CH:11][C:4]=2[N:3]=1.[Cl:18][C:19]1[CH:24]=[CH:23][C:22]([C:25]2[CH:26]=[CH:27][C:28]([C:31]#[CH:32])=[N:29][CH:30]=2)=[CH:21][CH:20]=1>>[Cl:18][C:19]1[CH:20]=[CH:21][C:22]([C:25]2[CH:26]=[CH:27][C:28]([C:31]#[C:32][C:2]3[N:6]([CH3:7])[C:5]4[CH:8]=[CH:9][C:10]([CH2:12][N:13]5[CH2:17][CH2:16][CH2:15][CH2:14]5)=[CH:11][C:4]=4[N:3]=3)=[N:29][CH:30]=2)=[CH:23][CH:24]=1

참가 물질

3

반응물 2

HCID 578453285-(4-Chloro-phenyl)-2-ethynyl-pyridineHCID 69077347HCID 69077347, 화합물

생성물 1

HCID 59835855HCID 59835855, 화합물

실험 절차

Prepared according to general working method I from 2-iodo-1-methyl-5-pyrrolidin-1-ylmethyl-1H-benzimidazole (100 mg, 0.29 mmol) and 5-(4-chloro-phenyl)-2-ethynyl-pyridine (68 mg, 0.32 mmol).

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-2234233dbac14475adaafbb9b817f41b
출처 데이터셋
uspto-grants-2013_12
특허 번호
US08618132B2

반응 노트

불러오는 중…