4-(Propan-2-yl)-3-sulfamoylbenzoic acid → 4-Isopropyl-N-[2-methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenyl]-3-sulfamoyl-benzamide
반응식
[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH2:19].[CH:20]([C:23]1[CH:31]=[CH:30][C:26]([C:27](O)=[O:28])=[CH:25][C:24]=1[S:32](=[O:35])(=[O:34])[NH2:33])([CH3:22])[CH3:21]>>[CH:20]([C:23]1[CH:31]=[CH:30][C:26]([C:27]([NH:19][C:3]2[CH:4]=[CH:5][C:6]([N:8]3[CH2:12][CH2:11][CH:10]([N:13]4[CH2:17][CH2:16][CH2:15][CH:14]4[CH3:18])[CH2:9]3)=[CH:7][C:2]=2[CH3:1])=[O:28])=[CH:25][C:24]=1[S:32](=[O:35])(=[O:34])[NH2:33])([CH3:22])[CH3:21]참가 물질
3
실험 절차
The title compound was prepared in a manner substantially the same as example 1 by coupling 2-methyl-4-(2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-phenylamine with 4-isopropyl-3-sulfamoyl-benzoic acid. MS: 485.3 (M+H).
출처 및 근거
- ORD 기록
- ord-1a4b48fdf0d2495ea3d455ffed06f281
- 출처 데이터셋
- uspto-grants-2013_12