4-(1H-1,2,4-Triazol-1-yl)benzoic acid → N-[2-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenyl]-4-[1,2,4]triazol-1-yl-benzamide

HRID 1916963노트

반응식

HRID 1916963 반응식
[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH2:19].[N:20]1([C:25]2[CH:33]=[CH:32][C:28]([C:29](O)=[O:30])=[CH:27][CH:26]=2)[CH:24]=[N:23][CH:22]=[N:21]1>>[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH:19][C:29](=[O:30])[C:28]1[CH:27]=[CH:26][C:25]([N:20]2[CH:24]=[N:23][CH:22]=[N:21]2)=[CH:33][CH:32]=1

참가 물질

3

반응물 2

HCID 7365314-(1H-1,2,4-Triazol-1-yl)benzoic acidHCID 594018302-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenylamine

생성물 1

HCID 25266935N-[2-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenyl]-4-[1,2,4]triazol-1-yl-benzamide

실험 절차

The title compound was prepared in a manner substantially the same as example 1 by coupling 2-methyl-4-(2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-phenylamine with 4-[1,2,4]triazol-1-yl-benzoic acid. MS: 431.3 (M+H).

출처 및 근거

ORD 기록
ord-db0984a43c3b4b279b4705a391fab916
출처 데이터셋
uspto-grants-2013_12
특허 번호
US08618159B2

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