Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
L-Malic Acid → Sunitinib Malate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | L-Malic Acid | HCID 222656 | — |
| 반응물 | Sunitinib | HCID 5329102 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | Sunitinib Malate | HCID 6456015 | — |
반응 단계
Sunitinib base (600 mg) was dissolved in pyridine (5 ml) at 100° C. and L-malic acid (230 mg) was added to the hot solution. Slight heating provided clear solution. Sunitinib malate was formed overnight at 20° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08618309B2 |
| 출처 데이터셋 | uspto-grants-2013_12 |
| ORD ID | ord-d5e4d1852a6b449f8fd5222a74ae2d90 |
| 출처 메모 | uspto-grants-2013_12 |