m-Chlorophenethylic alcohol → 5-[2-(3-Chloro-phenyl)-ethoxy]-nicotinic Acid Ethyl Ester

HRID 1918351

반응식

HRID 1918351 반응식
[CH2:1]([O:3][C:4](=[O:12])[C:5]1[CH:10]=[C:9]([OH:11])[CH:8]=[N:7][CH:6]=1)[CH3:2].[Cl:13][C:14]1[CH:15]=[C:16]([CH2:20][CH2:21]O)[CH:17]=[CH:18][CH:19]=1>>[CH2:1]([O:3][C:4](=[O:12])[C:5]1[CH:10]=[C:9]([O:11][CH2:21][CH2:20][C:16]2[CH:17]=[CH:18][CH:19]=[C:14]([Cl:13])[CH:15]=2)[CH:8]=[N:7][CH:6]=1)[CH3:2]

참가 물질

3

실험 절차

5-Hydroxy-nicotinic acid ethyl ester and 2-(3-chlorophenyl)ethanol were etherified in a Mitsunobu reaction in analogy to step 3 of example 3 to yield the title compound.

출처 및 근거

ORD 기록
ord-c83b45f328be439f811ad62c3b1df508
출처 데이터셋
uspto-grants-2013_12
특허 번호
US08618304B2

연결된 노트

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