Isopropyl iodide → 9H-Fluorene, 9-(1-methylethyl)-

HRID 1918426노트

반응식

HRID 1918426 반응식
[CH:1]1[C:13]2[CH2:12][C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[CH:4]=[CH:3][CH:2]=1.[Li][CH2:15][CH2:16][CH2:17]C.IC(C)C.OC1O[C@@H](CO)[C@H](O)[C@H](O)[C@H]1O>>[CH:16]([CH:12]1[C:11]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[C:5]2[C:13]1=[CH:1][CH:2]=[CH:3][CH:4]=2)([CH3:17])[CH3:15]

참가 물질

5

반응물 4

HCID 6362Isopropyl iodideHCID 6853FluoreneHCID 10219674L-AltroseHCID 178418339Butyllithium

생성물 1

HCID 186969H-Fluorene, 9-(1-methylethyl)-

실험 절차

Fluorene (15.0 g, 90.4 mmol), n-BuLi (48.1 ml, 120 mmol, 2.5 M in hexane), RX=2-iodopropane (14.0 ml, 139.6 mmol). 42 was isolated as a yellowish solid (18.7 g, quant.). The analytical data were identical with these to be found in the literature (M. A. Schmidt, H. G. Alt, W. Milius, J. Organomet. Chem. 1996, 525, 15).

후처리

  1. custom42 was isolated as a yellowish solid (18.7 g, quant.)

출처 및 근거

ORD 기록
ord-7e148871503b46838dc84cee25182137
출처 데이터셋
uspto-grants-2013_12
특허 번호
US08618328B2

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