6,6-Dimethyl-5,7-dioxaspiro(2.5)octane-4,8-dione → HCID 66832166, 화합물

HRID 1918583

반응식

HRID 1918583 반응식
CC1(C)[O:9][C:8](=[O:10])[C:5]2([CH2:7][CH2:6]2)[C:4](=[O:11])O1.[CH2:13]1[C:21]2[C:16](=[CH:17][C:18]([NH2:22])=[CH:19][CH:20]=2)[CH2:15][O:14]1>C(O)C>[CH2:13]1[C:21]2[C:16](=[CH:17][C:18]([N:22]3[CH2:6][CH2:7][CH:5]([C:8]([OH:9])=[O:10])[C:4]3=[O:11])=[CH:19][CH:20]=2)[CH2:15][O:14]1

참가 물질

4

반응물 2

HCID 797206,6-Dimethyl-5,7-dioxaspiro(2.5)octane-4,8-dioneHCID 124453391,3-Dihydro-2-benzofuran-5-amine

생성물 1

HCID 66832166HCID 66832166, 화합물수율 84%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

This compound was prepared according to general method 1 starting from 6,6-dimethyl-5,7-dioxaspiro[2.5]octane-4,8-dione (0.250 g; 1.45 mmol) and 1,3-dihydroisobenzofuran-5-amine (0.608 g; 4.36 mmol) in ethanol (3 mL). 1-(1,3-dihydroisobenzofuran-5-yl)-2-oxopyrrolidine-3-carboxylic acid 0.300 g (84%) was obtained as a white solid.

후처리

  1. customThis compound was prepared

출처 및 근거

ORD 기록
ord-96996e79c05247b094d34051687de30c
출처 데이터셋
uspto-grants-2013_12
특허 번호
US08618138B2

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