2-(Diethoxymethyl)-4,4-dimethylcyclohexanone → 1-(4-Chlorophenyl)-2-(diethoxymethyl)-4,4-dimethylcyclohexanol

HRID 1920368노트

반응식

HRID 1920368 반응식
[CH2:1]([O:3][CH:4]([O:14][CH2:15][CH3:16])[CH:5]1[CH2:10][C:9]([CH3:12])([CH3:11])[CH2:8][CH2:7][C:6]1=[O:13])[CH3:2].[Cl:17][C:18]1[CH:23]=[CH:22][C:21]([Mg]Br)=[CH:20][CH:19]=1>>[Cl:17][C:18]1[CH:23]=[CH:22][C:21]([C:6]2([OH:13])[CH2:7][CH2:8][C:9]([CH3:12])([CH3:11])[CH2:10][CH:5]2[CH:4]([O:3][CH2:1][CH3:2])[O:14][CH2:15][CH3:16])=[CH:20][CH:19]=1

참가 물질

3

반응물 2

HCID 580183412-(Diethoxymethyl)-4,4-dimethylcyclohexanoneHCID 178478191HCID 178478191, 화합물

생성물 1

HCID 580183391-(4-Chlorophenyl)-2-(diethoxymethyl)-4,4-dimethylcyclohexanol

실험 절차

reacting the 2-(diethoxymethyl)-4,4-dimethylcyclohexanone and 4-chlorophenyl magnesium bromide at about −60° C. to −10° C. to provide 1-(4-chlorophenyl)-2-(diethoxymethyl)-4,4-dimethylcyclohexanol and isolating or not isolating the 1-(4-chlorophenyl)-2-(diethoxymethyl)-4,4-dimethylcyclohexanol; and

후처리

  1. customat about −60° C. to −10° C.

출처 및 근거

ORD 기록
ord-681bfd5f2dba40f9807d20a9a1df7765
출처 데이터셋
uspto-grants-2012_05
특허 번호
US08168784B2

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