HCID 57733375, 화합물 → HCID 57733330, 화합물

HRID 1920750노트

반응식

HRID 1920750 반응식
[CH2:1]([O:3][C:4](=[O:16])[CH:5]=[C:6]1[CH2:11][CH2:10][N:9]([C:12]([CH3:15])([CH3:14])[CH3:13])[CH2:8][CH2:7]1)[CH3:2].[H][H]>C(O)C>[CH2:1]([O:3][C:4](=[O:16])[CH2:5][CH:6]1[CH2:7][CH2:8][N:9]([C:12]([CH3:15])([CH3:14])[CH3:13])[CH2:10][CH2:11]1)[CH3:2]

참가 물질

4

반응물 2

HCID 57733375HCID 57733375, 화합물HCID 178418361HCID 178418361, 화합물

생성물 1

HCID 57733330HCID 57733330, 화합물수율 78%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

To a solution of (1-tert-butyl-piperidin-4-ylidene)-acetic acid ethyl ester (5.1 g, 22.7 mmol) in ethanol (50 mL) 10% Pd/C (0.6 g) was added and the mixture was stirred under the hydrogen atmosphere (42 psi) at ambient temperature for 14 hours. The catalyst was removed by filtration, and the filtrate was concentrated to give the title (4.03 g, yield 78%), which was used in the next step directly.

후처리

  1. customThe catalyst was removed by filtration
  2. concentrationthe filtrate was concentrated
  3. customto give the title (4.03 g, yield 78%), which

출처 및 근거

ORD 기록
ord-3fd4387adce24d1f9ff5c2e7e14fbab6
출처 데이터셋
uspto-grants-2012_05
특허 번호
US08173639B2

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