Trifluoroacetic acid → HCID 67336664, 화합물

HRID 1921203노트

반응식

HRID 1921203 반응식
C(C(O)=O)(F)(F)F.[O:8]=[C:9]1[N:13](C(OC(C)(C)C)=O)[C:12]2[CH:21]=[CH:22][CH:23]=[CH:24][C:11]=2[N:10]1[CH:25]1[CH2:30][CH2:29][S:28][CH2:27][CH2:26]1>C(Cl)Cl>[S:28]1[CH2:27][CH2:26][CH:25]([N:10]2[C:11]3[CH:24]=[CH:23][CH:22]=[CH:21][C:12]=3[NH:13][C:9]2=[O:8])[CH2:30][CH2:29]1

참가 물질

4

반응물 2

HCID 6422Trifluoroacetic acidHCID 67338768HCID 67338768, 화합물

생성물 1

HCID 67336664HCID 67336664, 화합물

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

CF3CO2H (1 mL) was added to a solution of tert-butyl 2-oxo-3-tetrahydro-2H-thiopyran-4-yl-2,3-dihydro-1H-benzimidazole-1-carboxylate from Step A (210 mg, 0.628 mmol) in CH2Cl2 (3 mL). After 2 h, the mixture was concentrated in vacuo to give the title compound. MS: m/z=235 (M+1).

후처리

  1. concentrationthe mixture was concentrated in vacuo

출처 및 근거

ORD 기록
ord-eadad0323e23455bbf55d66393cba06c
출처 데이터셋
uspto-grants-2012_05
특허 번호
US08173655B2

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