Trifluoroacetic acid → HCID 59279572, 화합물

HRID 1921205노트

반응식

HRID 1921205 반응식
C(C(O)=O)(F)(F)F.[O:8]=[C:9]1[N:13]([CH2:14][C:15]([O:17]C(C)(C)C)=[O:16])[C:12]2[CH:22]=[CH:23][CH:24]=[CH:25][C:11]=2[N:10]1[CH:26]1[CH2:31][CH2:30][S:29][CH2:28][CH2:27]1>C(Cl)Cl>[O:8]=[C:9]1[N:13]([CH2:14][C:15]([OH:17])=[O:16])[C:12]2[CH:22]=[CH:23][CH:24]=[CH:25][C:11]=2[N:10]1[CH:26]1[CH2:31][CH2:30][S:29][CH2:28][CH2:27]1

참가 물질

4

반응물 2

HCID 6422Trifluoroacetic acidHCID 86619736HCID 86619736, 화합물

생성물 1

HCID 59279572HCID 59279572, 화합물

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

CF3CO2H (1 mL) was added to a solution of tert-butyl (2-oxo-3-tetrahydro-2H-thiopyran-4-yl-2,3-dihydro-1H-benzimidazol-1-yl)acetate from Step C (169 mg, 0.485 mmol) in CH2Cl2 (3 mL). After 3 h, the mixture was concentrated in vacuo to give the title compound. MS: m/z=293 (M+1).

후처리

  1. concentrationthe mixture was concentrated in vacuo

출처 및 근거

ORD 기록
ord-36d234a94f344987a6ee47263e486dcb
출처 데이터셋
uspto-grants-2012_05
특허 번호
US08173655B2

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