Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-(4-methyl-3-nitrophenyl)cyclopropanecarboxamide → N-(3-amino-4-methylphenyl)cyclopropanecarboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-(4-methyl-3-nitrophenyl)cyclopropanecarboxamide | HCID 4104437 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | N-(3-amino-4-methylphenyl)cyclopropanecarboxamide | HCID 24693537 | 94.8% |
반응 단계
N-(4-Methyl-3-nitrophenyl)cyclopropanecarboxamide (409 mg) was hydrogenated over 10% Pd/C (50% wet, 80 mg) at atmospheric pressure of hydrogen in MeOH (20 mL) for 5 hr. The catalyst was removed by filtration through Celite® pad and the filtrate was evaporated in vacuo to give N-(3-amino-4-methylphenyl)cyclopropanecarboxamide (335 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08173684B2 |
| 출처 데이터셋 | uspto-grants-2012_05 |
| ORD ID | ord-1148f2f8c34e49a9a37dc682729e6a91 |
| 출처 메모 | uspto-grants-2012_05 |