2-Amino-4'-methoxyacetophenone → 5'-Ethyl-2'-methyl-6'-oxo-1',6'-dihydro-[3,3']bipyridinyl-5-carboxylic acid [2-(4-methoxy-phenyl)-2-oxo-ethyl]-amide

HRID 1921524

반응식

HRID 1921524 반응식
[CH2:1]([C:3]1[C:8](=[O:9])[NH:7][C:6]([CH3:10])=[C:5]([C:11]2[CH:12]=[N:13][CH:14]=[C:15]([C:17]([OH:19])=O)[CH:16]=2)[CH:4]=1)[CH3:2].[CH3:20][O:21][C:22]1[CH:27]=[CH:26][C:25]([C:28](=[O:31])[CH2:29][NH2:30])=[CH:24][CH:23]=1>>[CH3:20][O:21][C:22]1[CH:23]=[CH:24][C:25]([C:28](=[O:31])[CH2:29][NH:30][C:17]([C:15]2[CH:16]=[C:11]([C:5]3[CH:4]=[C:3]([CH2:1][CH3:2])[C:8](=[O:9])[NH:7][C:6]=3[CH3:10])[CH:12]=[N:13][CH:14]=2)=[O:19])=[CH:26][CH:27]=1

참가 물질

3

반응물 2

HCID 4128892-Amino-4'-methoxyacetophenoneHCID 588087025'-Ethyl-2'-methyl-6'-oxo-1',6'-dihydro-[3,3']bipyridinyl-5-carboxylic acid

생성물 1

HCID 588085205'-Ethyl-2'-methyl-6'-oxo-1',6'-dihydro-[3,3']bipyridinyl-5-carboxylic acid [2-(4-methoxy-phenyl)-2-oxo-ethyl]-amide

실험 절차

Method 1, Example 205 is substantially repeated except for utilizing 5′-ethyl-2′-methyl-6′-oxo-1′,6′-dihydro-[3,3′]bipyridinyl-5-carboxylic acid and [2-(4-methoxy-phenyl)-2-oxo-ethyl]-amine to afford the title compound. MS: m/e=406 (M+H).

출처 및 근거

ORD 기록
ord-201d6b57df634de2ba5de3e4c716640f
출처 데이터셋
uspto-grants-2012_05
특허 번호
US08173682B2

연결된 노트

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