Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phenylacetyl chloride → N-(5-nitropyridin-2-yl)-2-phenylacetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phenylacetyl chloride | HCID 7679 | — |
| 반응물 | 2-Amino-5-nitropyridine | HCID 77888 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | N-(5-nitropyridin-2-yl)-2-phenylacetamide | HCID 4350143 | — |
반응 단계
A solution of 2-amino-5-nitropyridine (4.17 g, 30 mmol) in pyridine (30 mL) is stirred at rt and a solution of phenylacetyl chloride (4.64 g, 30 mmol) in THF (30 mL) is added dropwise. The mixture is stirred for 24 h and then poured into ice-water (250 mL) to afford a brown solid, which is used without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08173656B2 |
| 출처 데이터셋 | uspto-grants-2012_05 |
| ORD ID | ord-921ce141d60248e8b5c52203b19f8dd0 |
| 출처 메모 | uspto-grants-2012_05 |