2-Ethylbenzimidazole → HCID 59605718, 화합물
반응식
[CH2:1]([C:3]1[NH:4][C:5]2[CH:11]=[CH:10][CH:9]=[CH:8][C:6]=2[N:7]=1)[CH3:2].Cl[C:13]1[N:21]=[C:20]2[C:16]([N:17]=[C:18]([CH2:23][N:24]3[CH2:29][CH2:28][N:27]([C:30]([CH3:35])([CH2:33][OH:34])[CH2:31][OH:32])[CH2:26][CH2:25]3)[N:19]2[CH3:22])=[C:15]([N:36]2[CH2:41][CH2:40][O:39][CH2:38][CH2:37]2)[N:14]=1>>[CH2:1]([C:3]1[N:4]([C:13]2[N:21]=[C:20]3[C:16]([N:17]=[C:18]([CH2:23][N:24]4[CH2:25][CH2:26][N:27]([C:30]([CH3:35])([CH2:31][OH:32])[CH2:33][OH:34])[CH2:28][CH2:29]4)[N:19]3[CH3:22])=[C:15]([N:36]3[CH2:37][CH2:38][O:39][CH2:40][CH2:41]3)[N:14]=2)[C:5]2[CH:11]=[CH:10][CH:9]=[CH:8][C:6]=2[N:7]=1)[CH3:2]참가 물질
3
실험 절차
Following General Procedure I for Buchwald coupling, 2-ethylbenzimidazole and 2-(4-((2-chloro-9-methyl-6-morpholino-9H-purin-8-yl)methyl)piperazin-1-yl)-2-methylpropane-1,3-diol were reacted to give 440. LCMS m/z: 550.3 (MH+)
후처리
- customwere reacted
출처 및 근거
- ORD 기록
- ord-c0f8241fbb6841068b5e686887ffa10e
- 출처 데이터셋
- uspto-grants-2012_05