10-Methoxyibogamine → CID 44359441

HRID 1923463

반응식

HRID 1923463 반응식
[CH3:1][CH2:2][C@@H:3]1[C@@H:8]2[N:9]3[CH2:11][CH2:12][C:13]4[C:17]5[CH:18]=[C:19]([O:22]C)[CH:20]=[CH:21][C:16]=5[NH:15][C:14]=4[C@@H:7]2[CH2:6][C@@H:5]([CH2:10]3)[CH2:4]1.B(Br)(Br)Br.C(Cl)Cl>>[CH3:1][CH2:2][C@H:3]1[CH:8]2[N:9]3[CH2:11][CH2:12][C:13]4[C:17]5[CH:18]=[C:19]([OH:22])[CH:20]=[CH:21][C:16]=5[NH:15][C:14]=4[C@H:7]2[CH2:6][CH:5]([CH2:10]3)[CH2:4]1

참가 물질

3

반응물 2

HCID 44210810-Methoxyibogamine2회HCID 22277759Boron tribromide dichloromethane

생성물 1

HCID 44359441CID 44359441

실험 절차

Noribogaine is synthesized by the O-demethylation of ibogaine. This may be accomplished, for example, by reacting ibogaine with boron tribromide/methylene chloride at room temperature and then purifying the product using known procedures. At present, noribogaine may also be obtained from the National Institute on Drug Abuse (Rockville, Md.). The compound has the following structure:

후처리

  1. customat room temperature
  2. custompurifying the product

출처 및 근거

ORD 기록
ord-fa7f9182209342baa937effcdc7bf6cf
출처 데이터셋
uspto-grants-2012_05
특허 번호
US08178524B2

연결된 노트

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