4-bromo-1-methyl-1H-pyrazole-5-carbaldehyde → HCID 57743064, 화합물

HRID 1924236노트

반응식

HRID 1924236 반응식
CC1C(CN2CC(C3C=C(F)C=C(F)C=3F)CC2=O)=C(C)N(S(C2C=CC(C)=CC=2)(=O)=O)N=1.Cl.[NH2:35][CH2:36][CH:37]([C:44]1[CH:49]=[C:48]([F:50])[CH:47]=[C:46]([F:51])[C:45]=1[F:52])[CH2:38][C:39]([O:41]CC)=O.[Br:53][C:54]1[CH:55]=[N:56][N:57]([CH3:61])[C:58]=1[CH:59]=O>>[Br:53][C:54]1[CH:55]=[N:56][N:57]([CH3:61])[C:58]=1[CH2:59][N:35]1[CH2:36][CH:37]([C:44]2[CH:49]=[C:48]([F:50])[CH:47]=[C:46]([F:51])[C:45]=2[F:52])[CH2:38][C:39]1=[O:41]

참가 물질

4

반응물 3

HCID 27946344-bromo-1-methyl-1H-pyrazole-5-carbaldehydeHCID 53629161HCID 53629161, 화합물HCID 86631465HCID 86631465, 화합물

생성물 1

HCID 57743064HCID 57743064, 화합물

실험 절차

1-[(4-bromo-1-methyl-1H-pyrazol-5-yl)methyl]-4-(2,3,5-trifluorophenyl)pyrrolidin-2-one 182 is prepared as for compound x61 starting from ethyl 4-amino-3-(2,3,5-trifluorophenyl)butanoate hydrochloride x60 and 4-bromo-1-methyl-1H-pyrazole-5-carbaldehyde x65.

출처 및 근거

ORD 기록
ord-55b76db0256c4d539052dc81802eb1a6
출처 데이터셋
uspto-grants-2012_05
특허 번호
US08178533B2

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