(4-Methylphenyl)hydrazine → 1-(3-Methanesulfonyl-phenyl)-3-(2-p-tolyl-2H-pyrazol-3-yl)-1H-pyridazin-4-one

HRID 1924537

반응식

HRID 1924537 반응식
C[N:2](C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([S:20]([CH3:23])(=[O:22])=[O:21])[CH:15]=2)[N:8]=1)=O.[C:25]1([CH3:33])[CH:30]=[CH:29][C:28]([NH:31]N)=[CH:27][CH:26]=1>>[CH3:23][S:20]([C:16]1[CH:15]=[C:14]([N:9]2[CH:10]=[CH:11][C:12](=[O:13])[C:7]([C:5]3[N:31]([C:28]4[CH:29]=[CH:30][C:25]([CH3:33])=[CH:26][CH:27]=4)[N:2]=[CH:3][CH:4]=3)=[N:8]2)[CH:19]=[CH:18][CH:17]=1)(=[O:22])=[O:21]

참가 물질

3

반응물 2

HCID 10875(4-Methylphenyl)hydrazineHCID 593701713-((E)-3-Dimethylamino-acryloyl)-1-(3-methansulfonyl-phenyl)-1H-pyridazin-4-one

생성물 1

HCID 462189511-(3-Methanesulfonyl-phenyl)-3-(2-p-tolyl-2H-pyrazol-3-yl)-1H-pyridazin-4-one

실험 절차

Reaction of 3-((E)-3-dimethylamino-acryloyl)-1-(3-methansulfonyl-phenyl)-1H-pyridazin-4-one (A-7) and p-tolyl-hydrazine according to example 43 gave the desired product. MS: M=407.3 (M+H)+

출처 및 근거

ORD 기록
ord-f1416437830149a4ba7a69ee8815085b
출처 데이터셋
uspto-grants-2012_05
특허 번호
US08178538B2

연결된 노트

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