(3-Chloro-2-methylphenyl)hydrazine → 3-[2-(3-Chloro-2-methyl-phenyl)-2H-pyrazol-3-yl]-1-(3-methanesulfonyl-phenyl)-1H-pyridazin-4-one

HRID 1924545

반응식

HRID 1924545 반응식
C[N:2](C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([S:20]([CH3:23])(=[O:22])=[O:21])[CH:15]=2)[N:8]=1)=O.[Cl:25][C:26]1[C:27]([CH3:34])=[C:28]([NH:32]N)[CH:29]=[CH:30][CH:31]=1>>[Cl:25][C:26]1[C:27]([CH3:34])=[C:28]([N:32]2[C:5]([C:7]3[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]4[CH:19]=[CH:18][CH:17]=[C:16]([S:20]([CH3:23])(=[O:22])=[O:21])[CH:15]=4)[N:8]=3)=[CH:4][CH:3]=[N:2]2)[CH:29]=[CH:30][CH:31]=1

참가 물질

3

반응물 2

HCID 702863(3-Chloro-2-methylphenyl)hydrazineHCID 593701713-((E)-3-Dimethylamino-acryloyl)-1-(3-methansulfonyl-phenyl)-1H-pyridazin-4-one

생성물 1

HCID 462188243-[2-(3-Chloro-2-methyl-phenyl)-2H-pyrazol-3-yl]-1-(3-methanesulfonyl-phenyl)-1H-pyridazin-4-one

실험 절차

Reaction of 3-((E)-3-dimethylamino-acryloyl)-1-(3-methansulfonyl-phenyl)-1H-pyridazin-4-one (A-7) and (3-chloro-2-methyl-phenyl)-hydrazine according to example 43 gave the desired product. MS: M=441.0 (M)+

출처 및 근거

ORD 기록
ord-ee57c72b14c84a3b885f858196c6818a
출처 데이터셋
uspto-grants-2012_05
특허 번호
US08178538B2

연결된 노트

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