6-Fluoro-4-hydrazinyl-2-methyl-quinoline → 3-{3-[2-(6-Fluoro-2-methyl-quinolin-4-yl)-2H-pyrazol-3-yl]-4-oxo-4H-pyridazin-1-yl}-N,N-dimethyl-benzenesulfonamide

HRID 1924664노트

반응식

HRID 1924664 반응식
CN(C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:15]=[C:16]([S:20]([N:23]([CH3:25])[CH3:24])(=[O:22])=[O:21])[CH:17]=[CH:18][CH:19]=2)[N:8]=1)=O.[F:27][C:28]1[CH:29]=[C:30]2[C:35](=[CH:36][CH:37]=1)[N:34]=[C:33]([CH3:38])[CH:32]=[C:31]2[NH:39][NH2:40]>>[F:27][C:28]1[CH:29]=[C:30]2[C:35](=[CH:36][CH:37]=1)[N:34]=[C:33]([CH3:38])[CH:32]=[C:31]2[N:39]1[C:5]([C:7]2[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]3[CH:15]=[C:16]([S:20]([N:23]([CH3:25])[CH3:24])(=[O:22])=[O:21])[CH:17]=[CH:18][CH:19]=3)[N:8]=2)=[CH:4][CH:3]=[N:40]1

참가 물질

3

반응물 2

HCID 4932356-Fluoro-4-hydrazinyl-2-methyl-quinolineHCID 593701633-[3-((E)-3-Dimethylamino-acryloyl)-4-oxo-4H-pyridazin-1-yl]-N,N-dimethyl-benzenesulfonamide

생성물 1

HCID 593700913-{3-[2-(6-Fluoro-2-methyl-quinolin-4-yl)-2H-pyrazol-3-yl]-4-oxo-4H-pyridazin-1-yl}-N,N-dimethyl-benzenesulfonamide

실험 절차

The product was obtained starting from 3-[3-((E)-3-Dimethylamino-acryloyl)-4-oxo-4H-pyridazin-1-yl]-N,N-dimethyl-benzenesulfonamide (A-12) and (6-fluoro-2-methyl-quinolin-4-yl)-hydrazine according to the method described for example 91.

후처리

  1. customThe product was obtained

출처 및 근거

ORD 기록
ord-acb588e35189408dab38c8046f947e75
출처 데이터셋
uspto-grants-2012_05
특허 번호
US08178538B2

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