5-Hydrazinylquinoline → 1-(3-Difluoromethoxy-phenyl)-3-(2-quinolin-5-yl-2H-pyrazol-3-yl)-1H-pyridazin-4-one
반응식
[F:1][CH:2]([F:24])[O:3][C:4]1[CH:5]=[C:6]([N:10]2[CH:15]=[CH:14][C:13](=[O:16])[C:12]([C:17](=O)/[CH:18]=[CH:19]/[N:20](C)C)=[N:11]2)[CH:7]=[CH:8][CH:9]=1.[N:25]1[C:34]2[C:29](=[C:30]([NH:35]N)[CH:31]=[CH:32][CH:33]=2)[CH:28]=[CH:27][CH:26]=1>>[F:1][CH:2]([F:24])[O:3][C:4]1[CH:5]=[C:6]([N:10]2[CH:15]=[CH:14][C:13](=[O:16])[C:12]([C:17]3[N:35]([C:30]4[CH:31]=[CH:32][CH:33]=[C:34]5[C:29]=4[CH:28]=[CH:27][CH:26]=[N:25]5)[N:20]=[CH:19][CH:18]=3)=[N:11]2)[CH:7]=[CH:8][CH:9]=1참가 물질
3
실험 절차
The product was obtained starting from 1-(3-Difluoromethoxy-phenyl)-3-((E)-3-dimethylamino-acryloyl)-1H-pyridazin-4-one (A-10) and quinolin-5-yl-hydrazine according to the method described for example 91. MS: M=432.2 (M+H)+
후처리
- customThe product was obtained