2,5-Difluorophenylhydrazine → 3-{3-[2-(2,5-Difluoro-phenyl)-2H-pyrazol-3-yl]-4-oxo-4H-pyridazin-1-yl}-benzonitrile

HRID 1924742노트

반응식

HRID 1924742 반응식
C[N:2](C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:15]=[C:16]([CH:19]=[CH:20][CH:21]=2)[C:17]#[N:18])[N:8]=1)=O.[F:23][C:24]1[CH:29]=[CH:28][C:27]([F:30])=[CH:26][C:25]=1[NH:31]N>>[F:23][C:24]1[CH:29]=[CH:28][C:27]([F:30])=[CH:26][C:25]=1[N:31]1[C:5]([C:7]2[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]3[CH:15]=[C:16]([CH:19]=[CH:20][CH:21]=3)[C:17]#[N:18])[N:8]=2)=[CH:4][CH:3]=[N:2]1

참가 물질

3

반응물 2

HCID 5889572,5-DifluorophenylhydrazineHCID 59370150HCID 59370150, 화합물

생성물 1

HCID 593701583-{3-[2-(2,5-Difluoro-phenyl)-2H-pyrazol-3-yl]-4-oxo-4H-pyridazin-1-yl}-benzonitrile

실험 절차

The product was obtained starting from 3-[3-((E)-3-Dimethylamino-acryloyl)-4-oxo-4H-pyridazin-1-yl]-benzonitrile (A-19) and 2,5-difluoro-phenylhydrazine according to the method described for example 91. MS: M=376.2 (M+H)+

후처리

  1. customThe product was obtained

출처 및 근거

ORD 기록
ord-29bde79977ca4073b3310d5a090c3cec
출처 데이터셋
uspto-grants-2012_05
특허 번호
US08178538B2

반응 노트

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