Trifluoroacetic acid → Hexahydrocyclopenta(c)pyrrol-5(1H)-one

HRID 1925072노트

반응식

HRID 1925072 반응식
C(OC([N:8]1[CH2:12][CH:11]2[CH2:13][C:14](=[O:16])[CH2:15][CH:10]2[CH2:9]1)=O)(C)(C)C.FC(F)(F)C(O)=O>ClCCl>[CH2:9]1[CH:10]2[CH2:15][C:14](=[O:16])[CH2:13][CH:11]2[CH2:12][NH:8]1

참가 물질

4

반응물 2

HCID 6422Trifluoroacetic acidHCID 10998690tert-Butyl 5-oxohexahydrocyclopenta(c)pyrrole-2(1H)-carboxylate

생성물 1

HCID 46911901Hexahydrocyclopenta(c)pyrrol-5(1H)-one

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

reacting starting material 5-oxo-hexahydro-cyclopenta[c]pyrrole-2-carboxylic acid tert-butyl ester (I-1a) with trifluoroacetic acid in the solvent of dichloromethane in an ice-water bath to obtain hexahydro-cyclopenta[c]pyrrol-5-one triflutate (I-1b);

출처 및 근거

ORD 기록
ord-8c1cbdffad434e8a81e4705f0b105b40
출처 데이터셋
uspto-grants-2012_05
특허 번호
US08178575B2

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