Thionyl Chloride → 4-Methoxy-3-nitrobenzoyl chloride

반응식

[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([C:7](O)=[O:8])=[CH:5][C:4]=1[N+:12]([O-:14])=[O:13].S(Cl)([Cl:17])=O>>[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]([Cl:17])=[O:8])=[CH:5][C:4]=1[N+:12]([O-:14])=[O:13]

참가 물질

반응물 2

HCID 24386Thionyl Chloride

HCID 666404-Methoxy-3-nitrobenzoic acid

생성물 1

HCID 123754634-Methoxy-3-nitrobenzoyl chloride

실험 절차

4-methoxy-3-nitrobenzoic acid (10.0 g, 0.051 mol), and thionyl chloride (25 g, 0.212 mol), were refluxed together for 24 h. The reaction mixture was cooled to RT and concentrated to dryness. The off-white solid was carried onto the next step.

후처리

concentrationconcentrated to dryness

출처 및 근거

ORD 기록: ord-153dd7436cdd4bf28126e895d90e9318
출처 데이터셋: uspto-grants-2012_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08178557B2

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