참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Ethylamine | HCID 6341 | — |
| 반응물 | Tert-Butylamine | HCID 6385 | — |
| 반응물 | Acetylacetone | HCID 31261 | — |
| 반응물 | 5-Methyl hydrogen L-glutamate | HCID 68662 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | L-Theanine | HCID 439378 | 66.7% |
반응 단계
First, 5.0 g (31 mmol) of L-glutamic acid-γ-methyl ester was suspended in 15 mL of methanol. To this, 3.4 g (34 mmol) of acetylacetone and 2.3 g (31 mmol) of t-butylamine were added. The mixture was heated at 60° C. for 2 hours. Subsequently, 20 g (310 mmol) of 70% ethylamine was added to the mixture and the same procedure as in Example 1 was performed to obtain 3.6 g of theanine (yield: 66.7%). The obtained theanine had the same purity as high as in Example 1.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08178722B2 |
|---|
| 출처 데이터셋 | uspto-grants-2012_05 |
|---|
| ORD ID | ord-185e19505cb543bf9d781bbd31429b38 |
|---|
| 출처 메모 | uspto-grants-2012_05 |
|---|
