2,5-Dichloro-1,3-benzothiazole → 2-Chloro-7-methyl-1,3-benzothiazole
반응식
F[C:2]1[C:8]([CH3:9])=[CH:7][CH:6]=[CH:5][C:3]=1[NH2:4].SC1SC2C(C)=CC=CC=2N=1.[Cl:21][C:22]1[S:23]C2C=CC(Cl)=CC=2N=1>>[Cl:21][C:22]1[S:23][C:2]2[C:8]([CH3:9])=[CH:7][CH:6]=[CH:5][C:3]=2[N:4]=1참가 물질
4
반응 조건
- 온도
- 180 °C
실험 절차
The title compound was prepared from 2-fluoro-3-methylaniline via 2-mercapto-7-methyl-1,3-benzothiazole as described for 2,5-dichloro-1,3-benzothiazole except that in the first step the reaction mixture was heated to 180° C. for 24 h in a sealed tube.
출처 및 근거
- ORD 기록
- ord-485efb7d20e24fa096649e1404ecc564
- 출처 데이터셋
- uspto-grants-2012_05
- 특허 번호
- US08178668B2
반응 노트
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