6-Chloro-m-anisidine → 2-Iodo-5-methoxy-1,3-benzothiazole

HRID 1926414노트

반응식

HRID 1926414 반응식
F[C:2]1[C:10]2[S:9][C:8]([I:11])=[N:7][C:6]=2[CH:5]=[CH:4][CH:3]=1.FC1C(F)=CC=CC=1N.ClC1C=C[C:26]([O:29]C)=CC=1N>>[I:11][C:8]1[S:9][C:10]2[CH:2]=[CH:3][C:4]([O:29][CH3:26])=[CH:5][C:6]=2[N:7]=1

참가 물질

4

반응물 3

HCID 754606-Chloro-m-anisidineHCID 782782,3-DifluoroanilineHCID 675211807-Fluoro-2-iodobenzo[d]thiazole

생성물 1

HCID 189669722-Iodo-5-methoxy-1,3-benzothiazole

실험 절차

The title compound was prepared following the route for 7-fluoro-2-iodo-1,3-benzothiazole from 2,3-difluoroaniline, starting from 2-chloro-5-methoxyaniline and conducting the first step at 150° C. for 16 h.

후처리

  1. customat 150° C.
  2. customfor 16 h.

출처 및 근거

ORD 기록
ord-9ac711b8b2eb44a5aff8e660f566aa97
출처 데이터셋
uspto-grants-2012_05
특허 번호
US08178668B2

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