Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Bis(acetoxy)iodobenzene → 4-tert-Butylcyclohexanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Bis(acetoxy)iodobenzene | HCID 21865429 | — |
| 반응물 | 2,6,6-Trimethyl-3,3-bis(2,6,6-trimethyl-3-bicyclo[3.1.1]hept-1-enyl)bicyclo[3.1.1]hept-1-ene | HCID 53472035 | — |
| 용매 | Carbon Tetrachloride | HCID 5943 | — |
| 생성물 | 4-tert-Butylcyclohexanone | HCID 7392 | — |
반응 단계
To a 4-t-butylcyclohexane-1,1-dihydroperoxide and terpinene (trapping reagent) in a stirred room temperature solution of carbon tetrachloride was added, over a period of five to ten minutes, a solution of bisacetoxyiodobenzene (BAIB) in carbon tetrachloride. Rapid bubbling commenced upon addition of the BAIB solution and ceased within a few minutes after addition was completed. Stirring was continued for 0.5 h, after which the solution was filtered through a plug of silica, which was washed with CH2Cl2. The residue obtained upon concentration was purified by column chromatography on silica gel to give 4-t-butyl cyclohexanone and the trapping product ascaridole (endoperoxide of terpinene).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08182785B2 |
| 출처 데이터셋 | uspto-grants-2012_05 |
| ORD ID | ord-37ba5328c74f4ce7aa6f8813dc87a875 |
| 출처 메모 | uspto-grants-2012_05 |