Methyl propiolate → CGP-47292 methyl ester

반응식

[N:1]([CH2:4][C:5]1[C:10]([F:11])=[CH:9][CH:8]=[CH:7][C:6]=1[F:12])=[N+:2]=[N-:3].[C:13]([O:17][CH3:18])(=[O:16])[C:14]#[CH:15]>>[F:12][C:6]1[CH:7]=[CH:8][CH:9]=[C:10]([F:11])[C:5]=1[CH2:4][N:1]1[CH:15]=[C:14]([C:13]([O:17][CH3:18])=[O:16])[N:3]=[N:2]1

참가 물질

반응물 2

HCID 13536Methyl propiolate

HCID 108883232-(Azidomethyl)-1,3-difluorobenzene

생성물 1

HCID 22716778CGP-47292 methyl ester

실험 절차

reacting 2-(azidomethyl)-1,3-difluorobenzene of formula III with methyl propiolate to obtain methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylate of formula IV; and

출처 및 근거

ORD 기록: ord-cef56d85de904ec5ad5e2c719e3ba77a
출처 데이터셋: uspto-grants-2012_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08183269B2

반응 노트

불러오는 중…