Ammonia → Rufinamide
반응식
[F:1][C:2]1[CH:17]=[CH:16][CH:15]=[C:14]([F:18])[C:3]=1[CH2:4][N:5]1[CH:9]=[C:8]([C:10](OC)=[O:11])[N:7]=[N:6]1.[NH3:19]>>[CH:16]1[CH:15]=[C:14]([F:18])[C:3]([CH2:4][N:5]2[N:6]=[N:7][C:8]([C:10]([NH2:19])=[O:11])=[CH:9]2)=[C:2]([F:1])[CH:17]=1참가 물질
3
실험 절차
reacting methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylate of formula IV with ammonia to obtain rufinamide of formula I.
출처 및 근거
- ORD 기록
- ord-79c7c4f2988d466e87a620446bf0b5ba
- 출처 데이터셋
- uspto-grants-2012_05
- 특허 번호
- US08183269B2
반응 노트
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