Piperidin-4-ol → 1-(Imidazole-1-sulfonyl)-piperidin-4-ol

HRID 1928781

반응식

HRID 1928781 반응식
[OH:1][CH:2]1[CH2:7][CH2:6][NH:5][CH2:4][CH2:3]1.FC(F)(F)S([O-])(=O)=O.[N:16]1([S:21](N2C=C[NH+](C)C2)(=[O:23])=[O:22])[CH:20]=[CH:19][N:18]=[CH:17]1>>[N:16]1([S:21]([N:5]2[CH2:6][CH2:7][CH:2]([OH:1])[CH2:3][CH2:4]2)(=[O:23])=[O:22])[CH:20]=[CH:19][N:18]=[CH:17]1

참가 물질

3

반응물 2

HCID 79341Piperidin-4-olHCID 866341663-(1H-Imidazol-1-ylsulfonyl)-1-methyl-1H-imidazolium trifluoromethanesulfonate

생성물 1

HCID 689166431-(Imidazole-1-sulfonyl)-piperidin-4-ol

실험 절차

1-(Imidazole-1-sulfonyl)-piperidin-4-ol was prepared in accordance with step A of the general method described in example 76 from 4-hydroxypiperidin and 3-(1H-imidazol-1-ylsulfonyl)-1-methyl-1H-imidazolium trifluoromethanesulfonate; MS: m/e=232.5 (M+H+).

출처 및 근거

ORD 기록
ord-8bfd7055ed114811a6b9af08fa9d39af
출처 데이터셋
uspto-grants-2012_05
특허 번호
US08183380B2

연결된 노트

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