2-Chloro-6-nitroquinoline → Rac-n2-(6-fluoro-indan-1-yl)-quinoline-2,6-diamine

반응식

Cl[C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([N+:12]([O-])=O)[CH:8]=2)[N:3]=1.[F:15][C:16]1[CH:24]=[C:23]2[C:19]([CH2:20][CH2:21][CH:22]2[NH2:25])=[CH:18][CH:17]=1>>[F:15][C:16]1[CH:24]=[C:23]2[C:19]([CH2:20][CH2:21][CH:22]2[NH:25][C:2]2[CH:11]=[CH:10][C:9]3[C:4](=[CH:5][CH:6]=[C:7]([NH2:12])[CH:8]=3)[N:3]=2)=[CH:18][CH:17]=1

참가 물질

반응물 2

HCID 109217232-Chloro-6-nitroquinoline

HCID 154081276-Fluoro-2,3-dihydro-1H-inden-1-amine

생성물 1

HCID 68639984Rac-n2-(6-fluoro-indan-1-yl)-quinoline-2,6-diamine

실험 절차

The title compound was prepared in accordance with the general method described in example 2 from 2-chloro-6-nitro-quinoline and rac-6-fluoro-indan-1-ylamine (CAS no: 168902-77-0); MS: m/e=294.3 (M+H+).

출처 및 근거

ORD 기록: ord-962c08492cd34907ba9850af4453c2cf
출처 데이터셋: uspto-grants-2012_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08183380B2

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