Aniline → HCID 59152268, 화합물

HRID 1931413노트

반응식

HRID 1931413 반응식
FC(F)(F)C(O)=O.[F:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]2[N:16]=[C:17]([O:20][CH2:21][C:22]([OH:24])=O)[S:18][CH:19]=2)=[CH:11][CH:10]=1.[NH2:25][C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1>>[F:8][C:9]1[CH:10]=[CH:11][C:12]([C:15]2[N:16]=[C:17]([O:20][CH2:21][C:22]([NH:25][C:26]3[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=3)=[O:24])[S:18][CH:19]=2)=[CH:13][CH:14]=1

참가 물질

3

반응물 2

HCID 6115AnilineHCID 68536712HCID 68536712, 화합물

생성물 1

HCID 59152268HCID 59152268, 화합물

실험 절차

The title compound was prepared analogously as described in Example 30(d) from 100 mg (0.27 mmol) of [4-(4-fluoro-phenyl)-thiazol-2-yloxy]-acetic acid trifluoroacetic acid salt and 50.7 mg (0.54 mmol) of aniline. Yield: 7.6 mg.

출처 및 근거

ORD 기록
ord-a9cc84e2d7fa4aeaaf6495de5729ebc4
출처 데이터셋
uspto-grants-2012_05
특허 번호
US08188291B2

반응 노트

불러오는 중…