2-chloro-5-isocyanatopyridine → HCID 44218107, 화합물

반응식

[C@H:1]1([NH:10][C:11]2[CH:20]=[CH:19][C:18]3[C:13](=[CH:14][CH:15]=[C:16]([NH2:21])[CH:17]=3)[N:12]=2)[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1.[Cl:22][C:23]1[CH:28]=[CH:27][C:26]([N:29]=[C:30]=[O:31])=[CH:25][N:24]=1>>[Cl:22][C:23]1[N:24]=[CH:25][C:26]([NH:29][C:30]([NH:21][C:16]2[CH:17]=[C:18]3[C:13](=[CH:14][CH:15]=2)[N:12]=[C:11]([NH:10][C@H:1]2[C:9]4[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=4)[CH2:3][CH2:2]2)[CH:20]=[CH:19]3)=[O:31])=[CH:27][CH:28]=1

참가 물질

반응물 2

HCID 49612732-chloro-5-isocyanatopyridine

HCID 57860958(R)-N2-Indan-1-yl-quinoline-2,6-diamine

생성물 1

HCID 44218107HCID 44218107, 화합물

실험 절차

The title compound, MS: m/e=431.0 (M+H+), was prepared in accordance with the general method 4 of example 16 from (R)—N2-indan-1-yl-quinoline-2,6-diamine and 2-chloro-5-isocyanatopyridine.

출처 및 근거

ORD 기록: ord-24c6f496462c4ea4ad74572fa47cddc0
출처 데이터셋: uspto-grants-2012_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08188284B2

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