1-(2-Methoxyethyl)cyclopentane-1-carboxylic acid → HCID 69232792, 화합물
반응식
C[O:2][C:3](=[O:26])[C@H:4]([CH2:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]2[C:14](=[O:25])[N:15]([CH3:24])[C:16]([CH3:23])=[CH:17][C:18]=2[C:19]([F:22])([F:21])[F:20])=[CH:9][CH:8]=1)[NH2:5].[CH3:27][O:28][CH2:29][CH2:30][C:31]1([C:36](O)=[O:37])[CH2:35][CH2:34][CH2:33][CH2:32]1>>[CH3:27][O:28][CH2:29][CH2:30][C:31]1([C:36]([NH:5][C@H:4]([C:3]([OH:2])=[O:26])[CH2:6][C:7]2[CH:8]=[CH:9][C:10]([C:13]3[C:14](=[O:25])[N:15]([CH3:24])[C:16]([CH3:23])=[CH:17][C:18]=3[C:19]([F:22])([F:20])[F:21])=[CH:11][CH:12]=2)=[O:37])[CH2:35][CH2:34][CH2:33][CH2:32]1참가 물질
3
실험 절차
N-[[1-(2-methoxyethyl)cyclopentyl]carbonyl]-4-[1,6-dimethyl-4-(trifluoromethyl)-2-oxo-3-pyridinyl]-L-phenylalanine (mp 181-183° C.) was prepared from 4-[1,6-dimethyl-4-(trifluoromethyl)-2-oxo-3-pyridinyl]-L-phenylalanine methyl ester and 1-(2-methoxyethyl)cyclopentane carboxylic acid (obtained as described in WO 9910313) using the general procedures described in example 36. ES-HRMS m/e calcd for C26H31F3N2O5 (M+Na) 531.2077, found 531.2084.
출처 및 근거
- ORD 기록
- ord-a5ab3b6e6a744972833b2a3276efb619
- 출처 데이터셋
- uspto-grants-2002_05