Phosgene → 3-Cyclohexyloxyacryloyl chloride

HRID 1937058노트

반응식

[C:1]([Cl:4])(Cl)=[O:2].[CH:5]([O:7][CH:8]1[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1)=[CH2:6]>>[CH:8]1([O:7][CH:5]=[CH:6][C:1]([Cl:4])=[O:2])[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1

참가 물질

반응물 2

HCID 6371Phosgene

HCID 75129Cyclohexane, (ethenyloxy)-

생성물 1

HCID 539683613-Cyclohexyloxyacryloyl chloride수율 88%

반응 조건

온도: 50 °C

실험 절차

50 g (0.5 mol) of phosgene are condensed into a stirred apparatus fitted with −78° C.-cooling. Over a period of 3 hours, 50.5 g (0.4 mol) of cyclohexyl vinyl ether are subsequently added dropwise at 20° C. The mixture is then stirred at 50° C. for 5 hours. The excess phosgene is flushed out with nitrogen, and the crude product is worked up by distillation. At 110° C./2.5 mbar, 66.4 g (88%) of the product of value were obtained.

후처리

customcondensed into a stirred apparatus
customfitted with −78° C.-
temperaturecooling
customThe excess phosgene is flushed out with nitrogen
distillationthe crude product is worked up by distillation

출처 및 근거

ORD 기록: ord-dffae57b497f45268a46a5de7032e4f8
출처 데이터셋: uspto-grants-2002_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06392058B1

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