Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-Hydroxyphthalimide → 1-Acetylamino-3-adamantanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-Hydroxyphthalimide | HCID 10665 | — |
| 반응물 | 1-Acetamidoadamantane | HCID 64153 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 1-Acetylamino-3-adamantanol | HCID 2842792 | — |
| 생성물 | N-(4-oxo-1-adamantyl)acetamide | HCID 5338964 | — |
반응 단계
Mixture of 10 mmole 1-acetylaminoadamantane (Aldrich chemical Company, Inc.), 1 mmole of N-hydroxyphthalimide (NHPI), 0.05 mmole of vanadium(III)acetylacetonato (V(AA)3) and 25 mL of acetic acid was stirred under an oxygen atmosphere and the conditions represented in Table 1 (temperature and time). The products in the reaction mixture were analyzed by gas chromatography, and, as a result, 1-acetylamino-3-adamantanol (compound 1), 1-acetylamino-3,5-adamatanediol (compound 2) and 1-acetylamino-4-adamantanone (compound 3) were obtained with conversions and yields represented in Table 1.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06392104B1 |
| 출처 데이터셋 | uspto-grants-2002_05 |
| ORD ID | ord-82da175110b64bb58e630e4797e4cdaa |
| 출처 메모 | uspto-grants-2002_05 |